Mutations and Enzymes

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Description of a mutation

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Unexpected change in nucleotide order on DNA strand

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Type of mutation causing serious problems

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chromosomal mutation

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Mutation type: T-G-A-C-C-A to T-G-A-G-C-A

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Substitution

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Mutated DNA: TTACGCAAC

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Substitution mutation

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Mutation Example: ATT-TGA-GCC to ATT-GAG-CC

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Deletion - Frameshift

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DNA Mutation Example: TTA-CGC-AAG to TTC-GCA-AG

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Type: Deletion

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Mutation type:

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insertion

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Gene mutation type:

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Insertion frameshift

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Are all mutations bad?

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No

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Harmfulness of insertion/deletion mutations

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Change all codons downstream, altering amino acid sequence