Cell Cycle (AP BIO)

Front

What is the function of tumor suppressor genes?

Back

To inhibit the cell cycle and promote apoptosis.

Front

What happens if DNA damage is detected at the G2 checkpoint?

Back

The cell cycle stops until the DNA can be repaired or undergoes apoptosis.

Front

What role does p53 play in the cell cycle?

Back

It inhibits the CDK-cyclin complex when there is DNA damage.

Front

What is the consequence of mutations in proto-oncogenes?

Back

They lead to uncontrolled cell division.

Front

What is the primary function of the mitotic spindle during mitosis?

Back

To ensure chromosomes are properly segregated.

Front

Define the cell cycle.

Back

The series of events that take place in a cell leading to its division and replication.

Front

What are the main phases of the cell cycle?

Back

G1, S, G2, and M phases.

Front

What occurs during the S phase of the cell cycle?

Back

DNA replication takes place.

Front

What is apoptosis?

Back

Programmed cell death that occurs in multicellular organisms.

Front

What is the role of cyclins in the cell cycle?

Back

Cyclins are proteins that regulate the progression of the cell cycle by activating cyclin-dependent kinases (CDKs).