DNA Replication

Front

What are Okazaki fragments?

Back

Short segments of DNA synthesized on the lagging strand during DNA replication.

Front

On which strand of DNA do Okazaki fragments appear during replication?

Back

Lagging strand.

Front

Which enzyme unwinds the DNA double helix before replication?

Back

Helicase.

Front

What is the direction of DNA replication?

Back

5' to 3' direction.

Front

What does it mean that DNA strands are antiparallel?

Back

The two strands run in opposite directions; one runs 5' to 3' and the other runs 3' to 5'.

Front

What is the leading strand in DNA replication?

Back

The strand that is synthesized continuously in the same direction as the replication fork.

Front

What is the lagging strand in DNA replication?

Back

The strand that is synthesized discontinuously in short segments (Okazaki fragments) away from the replication fork.

Front

What enzyme adds free nucleotides to the growing DNA strand?

Back

DNA polymerase.

Front

What is the role of DNA ligase in DNA replication?

Back

To join Okazaki fragments together on the lagging strand.

Front

What is the replication fork?

Back

The Y-shaped region where the DNA double helix separates during replication.