Understanding Sickle Cell Anemia

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What is sickle cell anemia?

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A genetic blood disorder that affects the shape of red blood cells.

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NGSS.HS-LS3-1

NGSS.HS-LS3-2

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True or False: Sickle cell anemia is a genetic disorder.

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True

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NGSS.HS-LS3-1

NGSS.HS-LS3-2

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True or False: A person with sickle cell trait has two copies of the sickle cell gene.

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False

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NGSS.HS-LS3-1

NGSS.HS-LS3-2

Front

What causes sickle cell anemia?

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A mutation in the hemoglobin gene.

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NGSS.HS-LS3-1

NGSS.HS-LS3-2

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True or False: People with sickle cell anemia are immune to malaria.

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True

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NGSS.HS-LS3-2

NGSS.HS-LS4-2

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What shape do red blood cells take in sickle cell anemia?

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Sickle or crescent shape.

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NGSS.HS-LS1-1

NGSS.HS-LS3-2

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What is the inheritance pattern of sickle cell anemia?

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Autosomal recessive.

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NGSS.HS-LS3-1

NGSS.HS-LS3-2

Front

What is the role of hemoglobin in red blood cells?

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Hemoglobin carries oxygen from the lungs to the rest of the body.

Front

What are some symptoms of sickle cell anemia?

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Pain episodes, anemia, swelling in hands and feet, frequent infections.

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NGSS.MS-LS3-1

Front

How does sickle cell anemia affect blood flow?

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Sickle-shaped cells can block blood flow in small blood vessels.