Advances in Molecular Testing Methods

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What recent advances are changing the practice of clinical microbiology and infectious disease?

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Molecular testing methods.

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What technologies have complemented conventional culture methods in infectious disease diagnosis?

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Nucleic acid technologies.

Front

What types of microorganisms were molecular approaches previously limited to detecting?

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Slow-growing, difficult-to-cultivate, or uncultivatable microorganisms.

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What advancements have made molecular diagnostic testing adaptable for clinical laboratories?

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Automated nucleic acid extraction instrumentation and rapid PCR/target detection formats.

Front

What capabilities do some assays offer in molecular diagnostic testing?

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Detection, quantification, and mutation screening.

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Why may some assays be useful in screening for antimicrobial resistance?

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They can screen for antimicrobial resistance-associated mutations.