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Front

Pat is struggling with chronic migraines. His doctor recommends starting him on gabapentin, an FDA-approved medication for seizures, for his migraines, because some people have shown benefit. This prescription would be an example of:

Back

Off-label Use

Front

What is the therapeutic index of a new drug for chronic heart failure with a median effective dose of 7mg, median toxic dose of 18mg, and median lethal dose of 500mg, and is it considered to be in low therapeutic index?

Back

TI=2.57, not low