

AutoImmune Neurology
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13 questions
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1.
FLASHCARD QUESTION
Front
Postinfectious N-methyl-D-aspartate (NMDA) receptor encephalitis is most associated with which of the following viral infections? Cytomegalovirus, Herpes Simplex virus, Human Herpesvirus 6, Varicella Zoster virus, West Nile virus
Back
Herpes Simplex virus
2.
FLASHCARD QUESTION
Front
What antibody is most likely present in a case of autoimmune encephalitis in a 63 year-old man with symptoms of agitation, hallucinations, delusions, insomnia, hyperhidrosis, leg pain, and orthostatic leg myoclonus? Options: a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor, contacting-associated protein like 2 (CASPR2), dipeptidyl-peptidase-like protein (DPPX), Ig-like cell adhesion molecule 5 (IgLON5), myelin oligodendrocyte glycoprotein (MOG)
Back
contacting-associated protein like 2 (CASPR2)
3.
FLASHCARD QUESTION
Front
Which of the following systemic disorders can be the sole manifestation of paraneoplastic neurological autoimmunity? Barret Esophagus, Bronchospasm, Bundle Branch Block, GastroIntestinal PseudoObstruction, Neprholithiasis
Back
GastroIntestinal PseudoObstruction
4.
FLASHCARD QUESTION
Front
A 35 year old woman presents with nausea, vomiting, and intractable hiccups. MRI shows T2 hyperintensity and gadolinium contrast enhancement in the dorsal surface of the medulla at the caudal end of the fourth ventricle. Which of the following is the most likely diagnosis? Options: acute disseminated encephalomyelitis, multiple sclerosis, aquaporin-4 (AQP4) antibody-positive neuromyelitis optica spectrum disorder (NMOSD), Diffuse myelinoclastic sclerosis, myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD)
Back
aquaporin-4 (AQP4) antibody-positive neuromyelitis optica spectrum disorder (NMOSD)
5.
FLASHCARD QUESTION
Front
Which brain MRI abnormalities are more specific for multiple sclerosis?
Back
6.
FLASHCARD QUESTION
Front
Which of the following radiologic features is more suggestive of multiple sclerosis myelitis than aquaporin-4 (AQP4) antibody-positive neuromyelitis optic spectrum disorder (NMOSD) or Myelin Oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) myelitis? Options: axial H-sign, conus involvement, longitudinally extensive single lesion, marked cord swelling, multiple short lesions
Back
multiple short lesions
7.
FLASHCARD QUESTION
Front
Which of the following features of optic neuritis suggest myelin oligodendrocyte glycoprotein (MOG) antibody -associated disease (MOGAD) as the possible underlying etiology? anterior segment involvement with optic nerve sheath enhancement, chasmal involvement, homonymous hemianopia, posterior optic pathway involvement, short segment involvement with homogenous optic nerve enhancement
Back
anterior segment involvement with optic nerve sheath enhancement
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