1/28 Flashcard

Front

What property of water allows it to dissolve ions effectively?

Back

High dielectric constant.

Front

What distinguishes mixed noncompetitive inhibition from pure noncompetitive inhibition?

Back

Inhibitor has different affinities for E and ES.

Front

What do enzymes primarily do in biological systems?

Back

Lower the free energy of activation.

Front

What does the steady-state assumption in Michaelis-Menten kinetics imply?

Back

ES formation rate equals ES breakdown rate.

Front

What distinguishes ΔG from ΔG‡?

Back

ΔG‡ determines reaction rate.

Front

Define high dielectric constant in the context of water.

Back

A measure of water's ability to reduce the electrostatic forces between charged particles.

Front

Explain the concept of mixed noncompetitive inhibition.

Back

Inhibitor binds to both enzyme and enzyme-substrate complex with different affinities.

Front

What is the role of enzymes in biochemical reactions?

Back

Enzymes act as catalysts to speed up reactions by lowering activation energy.

Front

Describe the significance of the steady-state assumption in enzyme kinetics.

Back

It simplifies the analysis by assuming that the concentration of the enzyme-substrate complex remains constant.

Front

What is the relationship between ΔG and spontaneity of a reaction?

Back

A negative ΔG indicates a spontaneous reaction.