

Antigen processing and presentation
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University
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Practice Problem
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Hard
DR CHHABDA
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1 Slide • 11 Questions
1
Antigen processing and presentation

2
Multiple Choice
Which of the following DOES NOT play a role in antigen presentation
MHC Class I molecule
MHC Class II molecule
MHC Class III molecule
None of the above
3
Multiple Choice
Identify the structure
MHC Class II molecule
MHC Class I molecule
Ig G
IgA
4
Fill in the Blanks
Type answer...
5
Multiple Choice
Foreign antigens presented on class I MHC molecules...
stimulate other immune system cells to respond to the antigen.
stimulate macrophages to respond to the antigen.
stimulate cell destruction by macrophages.
stimulate cell destruction by activated T-cells.
6
Multiple Choice
The sequence for the processing of proteins produced within the cell is...
Proteins are broken into fragments, transported to the rough endoplasmic reticulum, fuse with a Golgi vesicle containing class II MHCs, and this complex is transported to the plasma membrane.
Proteins are broken into fragments within a vesicle, which fuses with a Golgi vesicle containing class I MHCs, and this complex is transported to the plasma membrane.
Proteins are broken into fragments, transported to the rough endoplasmic reticulum, combined with class I MHCs, move to the Golgi apparatus, then to the plasma membrane.
Proteins are broken into fragments, transported to the rough endoplasmic reticulum, combined with class II MHCs, move to the Golgi apparatus, then to the plasma membrane.
7
Multiple Choice
Fragments of foreign proteins are antibodies
true
false
8
Fill in the Blanks
Type answer...
9
Multiple Choice
choose the correct statement
All cells express class I MHC molecule
exogenous antigens are processed by endocytic pathway
class III MHC genes encode membrane bound proteins
MHC molecules are lipoproteins
10
Multiple Choice
CLIP IS
CLASS II ASSOCIATED INVARIANT CHAIN PEPTIDE
CLASS III ASSOCIATED INVARIANT CHAIN PEPTIDE
CLASS I ASSOCIATED INVARIANT CHAIN PEPTIDE
COMMON INVARIANT CHAIN PEPTIDE
11
Multiple Choice
Cross presentation of exogenous antigens is done by -------- as it has great advantage for the host.
B Cells
Dendritic Cells
T cells
NK cells
12
Multiple Choice
Fragments of foreign proteins are antibodies
true
false
Antigen processing and presentation

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