KA6a Gene Mutations

KA6a Gene Mutations

Katie Paget

Open Ended

What can you remember about mutations? What are they, can you name any types? Can you give any examples of diseases caused by mutation?

Multiple Choice

What type of point mutation is this?

• insertion

• deletion

• substitution

• inversion

Research terms

• silent mutation

• neutral mutation

• missense mutation

• nonsense mutation

• frameshift mutation

Multiple Choice

Sickle cell anaemia is a human condition that affects haemoglobin, reducing the blood’s ability to carry oxygen.

It is caused by a mutation that changes one adenine base to thymine. This results in one amino acid in haemoglobin being changed.

The mutation that causes sickle cell anaemia is

• deletion

• insertion

• substitution

• translocation

Multiple Choice

Normal-

AGA-TTC-ATA-GCG

Mutant-

AGA-TTC-AAT-AGC-G

• deletion frameshift

• insertion frameshift

• substitution

• nonsense

Multiple Choice

An original DNA segment is TTACGCAAG

Mutated DNA segment is TTCGCAAG.

This is an example of ___ mutation.

• Substitution

• Deletion

• Insertion

• Inversion

Multiple Choice

What is the correct mRNA strand from this DNA?
CAC-GTG-ACA-GCG

• GTG-CAC-TGT-CGC
• CAC-GUG-ACA-GCG
• GUG-CAC-UGU-CGC

Open Ended

Which parts of todays class are most difficult or confusing (which questions did I get wrong)? Have I written them all down to go back to?