6E: Mutations

6E: Mutations

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Multiple Select

Select all the statements that apply to mutations:

• Mutations are a source of genetic variation

• ALL mutations are passed down to the offspring

• Mutations are random

• Mutations are changes in DNA sequences

• Mutations are always bad

Multiple Choice

Mutated DNA sequences that can be passed from parent to offspring --

• occur in somatic cells (body cells)

• occur in gametic cells (sex cells)

• are rejected by meiosis

• only occur if the parent is exposed to harmful substances

Multiple Choice

6E: The survival of a species depends on its ability to adapt to changes in the environment. A species must be capable of surviving and reproducing despite changes to food sources, climate, or threats from predators. Which statement correctly describes a way that mutations increase the likelihood that a species will survive in a changing environment?

• Mutations are a source of variation in the species

• Mutations are the cause of disease in the species

• Mutations are not harmful when they occur in the somatic cells of the species

• Mutations are always passed on to subsequent generations of the species

Open Ended

6E Exposure to the building material asbestos (lung cancer) has been linked to certain types of cancers. Asbestos causes mutations in the p53 gene, which controls tumor suppression.

Would the people with cancer due to asbestos exposure pass the mutation to their offspring? EXPLAIN why or why not

Multiple Choice

Which shows a substitution mutation:

Original DNA: TTACATGG

• TTAGATGG

• TTAACATGG

• TTACAGG

• TTACATGG

Multiple Choice

Which shows a insertion mutation from the following DNA strand:

GATCATGTA

• GATCATCTA

• GATCATGGTA

• GATATGTA

• GATCATGTA

Multiple Choice

Which shows a deletion mutation from the following DNA sequence

CGTAAGATC

• CGTAGATC

• CGTAAGAATC

• CGTAGGATC

• CGTAAGATC

Multiple Choice

6E: A certain mutation in the gene for hemoglobin results in the red blood cells becoming sticky, rigid, and irregularly shaped. These irregularly shaped red blood cells block the flow of blood throughout the body. A single base mutation is responsible for these irregularly shaped blood cells. Which of these mutations most likely results in the mutated hemoglobin?

• Insertion

• Deletion

• Duplication

• Substitution

Open Ended

6E: Different types of mutations can occur in DNA. The diagram represents a type of mutation. Which statement describes the mutation in the diagram?

Open Ended

6E Sickle-shaped red blood cells result from a mutation in the gene that codes for hemoglobin. This mutation results in sickle-cell anemia. A partial sequence of bases from a normal hemoglobin gene and a sequence that results in sickle-cell anemia are shown.

What type of mutation is depicted in this sequence? HOW DO YOU KNOW!!!

Multiple Choice

Which of the following would result in a frameshift mutation?

• Insertions only

• Substitution only

• Deletion only

• Insertions and Deletions

Multiple Choice

A mutation in which only one nucleotide is altered is called a:

• Frameshift Mutation

• Deletion Mutation

• Point Mutation

• Insertion Mutation