Unit 4 Day 7- RNA Transcription

Unit 4 Day 7- DNA Transcription

By jack morgan

Open Ended

What are the five Nitrogenous Bases? (Just the first letter is fine)

Open Ended

Of the four bases used in DNA, what are the two different base pairs?

Today​, we will learn how DNA not only acts as a template for itself, but also for RNA

Yes​terday we learned about how DNA replicates itself, using each strand as a template for the new one.

Multiple Choice

The Nitrogenous Bases form the connections between strands of DNA, but what two molecules form the backbone of DNA?

• Glucose and Calcium

• Lactose and Potassium

• Ribose and Phosphate

• Sucrose and Nitrate

​The ​Central Dogma is the process by which DNA is transcribed into RNA, and then RNA is translated into proteins.

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​DNA gets all the credit for our traits, but its just the blueprint, Proteins are what actually produce our traits

Lets talk about the "Cen​tral

​ Dogma" of Molecular Biology

Trans​cription: ​occurs in the nucleus

Trans​lation: Occurs in the Cytoplasm

P​rotein Synthesis: Occurs in Ribosomes

What's the ​important part of real estate? Location, Location, Location

Making m​essanger RNA takes place in 3 steps

​ 1. Initiation

2. Elongation

3. Termination

Transc​ription: DNA ​directed synthesis of RNA (mRNA)

​mRNA will carry the genetic instructions from DNA through the cytoplasm to the ribosome where that specific protein will be made

• ​Deoxy​ribose is the sugar in the backbone

• ​Stranded

• Adenine, Thymine, Guanine, and Cytosine are Bases

DNA​

• Rib​ose is the sugar in the backbone

• ​Single Stranded

• Uracil replaces ​Thymine as the 4th nitrogenous base

  • ​A - U

  • G - C

RNA​

RNA vs DNA​ (E.O.C.)!!!!

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• ​First, the DNA has to be unzipped, just like in DNA replication

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​Then, we can begin Step 1: Initiation

Transcri​ption Mechanics​

Multiple Choice

What's the name of the enzyme that unzips DNA?

• Synthase

• Replicase

• Helicase

• Unziplicase

The Promotor Unit ​where RNA polymerase​ attaches to start making mRNA

Step 1​: Initiation

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During ​elongation, RNA polymerase adds complimentary nucleotides to the template DNA- JUST LIKE DNA REPLICATION

Step 2: ​Elongation

RNA transcription will end when ​RNA polymerase reaches the Terminator region of the DNA molecule

Step 3: Terminat​ion

Open Ended

Discuss with your group: Why might it be beneficial for RNA polymerase to only transcribe a portion of the DNA molecule instead of all of it?

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​ Any Questions?

Once transcription has been terminated, the mRNA is ready to leave the nucleus!