Chapter 2 Review

Multiple Choice

Chemotherapeutic agents are drugs that

• are used only to treat cancers

• replace normal body chemicals that are missing because of disease

• interfere with foreign cell functioning causing cell death, such as invading microorganisms or neoplasms

• stimulate the normal functioning of a cell

Multiple Choice

Receptor sites

• are a normal part of enzyme substrates

• are protein areas on cell membranes that react with specific chemicals

• can usually be stimulated by many different chemicals

• are responsible for all drug effects in the body

Multiple Choice

Selective toxicity is

• the ability of a drug to seek out a specific bacterial species or microorganism

• the ability of a drug to case only specific adverse effects

• the ability of a drug to cause fetal damage

• the ability of a drug to attack only those systems found in foreign or abnormal cells

Multiple Choice

When trying to determine why the desired therapeutic effect is not being seen with an oral drug, the nurse should consider

• the blood flow to muscle beds

• food altering the makeup of gastric juices

• the weight of the patient

• the temperature of the peripheral environment

Multiple Choice

Much of the biotransformation that occurs when a drug is taken occurs as part of

• the protein-binding effect of the drug

• the functioning of the renal system

• the first-pass effect through the liver

• the distribution of the drug to the reactive tissues

Multiple Choice

The half-life of a drug

• is determined by a balance of all pharmacokinetic processes

• is a constant factor for all drugs taken by a patient

• is only influenced by the fat distribution of the patient

• can be calculated with the use of a body surface nomogram