Metabolic Pathways HB SQA

Metabolic Pathways

​Higher Biology

Sophies Tutoring Caithness

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Metabolic pathways can be described as a series of ​

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reactions that start with ​

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and finish with an end ​

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Metabolic pathways are integrated and ​

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enzyme ​

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reactions within a cell.

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What does 'anabolic' mean?

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Give an example of an anabolic reaction.

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What does 'catabolic' mean?

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Give an example of a catabolic reaction

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Almost all pathways are reversible. Metabolic pathways can be reversible or ​irreversible. True or false?

Multiple Select

What do proteins found embedded in the membrane act as?

• Gates

• Pumps

• Pores

• Plates

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What is the site on the enzyme called where a substrate binds?

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If an enzyme is present, is the activation energy higher or lower?

Labeling

Label this diagram

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Activation energy without enzyme

Activation energy with enzyme

Open Ended

Discuss how the presence of an enzyme affects the reaction rate.

​https://www.bbc.co.uk/bitesize/guides/zwnffg8/revision/4

​Answer

​Watch this video for an insight into the effect of an enzyme on the reaction rate

Open Ended

Discuss how the effect of substrate concentration affects the reaction rate.

​Answer

​https://www.bbc.co.uk/bitesize/guides/zwnffg8/revision/4

​Watch this video for an insight on how substrate concentration affects the reaction rate

Open Ended

Discuss how changing pH levels affects the activity of an enzyme

​Answer

​https://www.bbc.co.uk/bitesize/guides/zwnffg8/revision/4

​Watch this video for an insight on how changing pH affects enzyme activity

Multiple Select

Which of these are types of inhibition?

• Competitive inhibition

• Non competitive inhibition

• Positive inhibition

• Feedback inhibition

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​

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inhibition occurs when an inhibitor molecule ​

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to the ​

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Of the enzyme and stops the substrate from binding. They can ​

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with the substrate because they have a ​similar​

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.

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​

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inhibition occurs when an inhibitor ​

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bind to the active site but does bind to a different part of the ​

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and changes the ​ ​

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Shape. This stops the substrate from binding to the enzyme and ​ ​

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reaction rate.

Open Ended

Discuss what is occurring at each line on this graph.

​Answer

​The graph levels off because all of the active sites are occupied with the substrate

​There is a gradual increase in reaction rate because competitive inhibitors occupy only some of the enzyme active sites.

​Most enzyme molecules have become inactive, but some are unaffected by the inhibitors, so the reaction rate remains low. An increase in substrate concentration does not increase reaction rate

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​​

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inhibition occurs when the end product in a metabolic pathway binds to an ​

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at the

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of the pathway. This process ​

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the metabolic pathway and so prevents further ​

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Of the end product until the end product concentration decreases.