Bell Ringer: Sickle Cell Pedigrees

Bell Ringer:
Sickle Cell Pedigrees

In humans, sickle cell disease is recessive. Individuals with sickle cell have irregular shaped blood that does not flow normally within the blood vessels. This can lead to tissues not getting enough oxygen and blood clots. Those who are carriers for sickle cell do not have major symptoms, but a simple test can reveal if a person is a carrier.

Match

Given the following genotypes, describe the phenotypes as either normal, carrier, or sickle cell disease.

• AA

• Aa

• aa

Normal

Carrier

Sickle Cell Disease

• Normal

• Carrier

• Sickle Cell Disease

Labeling

Examine the pedigree chart shown below. For each individual, drag the genotype in the square or circle.

Drag labels to their correct position on the image

aa

Aa

AA

Aa

Aa

Aa

AA

aa

aa

Aa

Fill in the Blanks

How many children did the original couple have?

Drag and Drop

What is the sex of the middle child?​

Placeholder

Drag these tiles and drop them in the correct blank above

Female

Male