AP Bio U5L11 Pedigree Analysis

Multiple Choice

A couple, individuals II-1 and II-2, come into a doctor's office to discuss having children. The man has Marfan's syndrome, an autosomal dominant disorder, that affects the connective tissue in the body. The woman does not have the syndrome. The doctor asks for a pedigree of the man's immediate relatives. What are the genotypes of the couple II-1 and II-2?

• II-1: aa

  II-2: aa

• II-1: AA

  II-2: AA

• II-1: aa

  II-2: Aa

• II-1: Aa

  II-2: Aa

Multiple Choice

Sickle cell anemia is autosomal recessive, which means someone affected by the disease must have a genotype that is (aa). Which parental cross will give the highest percentage of the recessive trait for sickle cell anemia being passed to their children?

• homozygous recessive and a heterozygous carrier

• homozygous dominant and a homozygous recessive

• two heterozygous carriers

• homozygous dominant and heterozygous carrier

Multiple Choice

Hemophilia is an X-linked recessive disorder. Which of the following sets of parents could produce a female with hemophilia?

Select all that apply.

• X^aX^a × X^AY

• X^AX^A × X^aY

• X^AX^a × X^aY

• X^aX^a × X^aY

Multiple Choice

In the following X-linked dominant pedigree, what is the genotype of individual I-1?

• AA

• X^AX^a

• X^AX^A

• aa