Introductory Module

Introductory Module - Quiz
Batch 34

​Faculty of Medicine
University of Kelaniya

Multiple Choice

1) What is the stage of the parasite shown in this stained thin blood film?

• a) Female gametocyte

• b) Male gametocyte

• c) Schizont

• d) Trophozoite

Multiple Choice

2) What type of necrosis is seen in this photomicrograph?

• a) Coagulative necrosis

• b) Liquefactive necrosis

• c) Caseous necrosis

• d) Fat necrosis

• e) Fibrinoid necrosis

Multiple Choice

   3) A 4-year-old child admitted to the Paediatric ward with excessive crying and high fever, was suspected to have meningitis. His CSF microscopy is given.

Sate the most likely pathogen.

• a)   Streptococcus agalactiae

• b)   Streptococcus pneumoniae

• c)  Neisseria meningitidis

• d)   Listeria monocytogenes

Multiple Choice

4) This 60-year-old man has been on treatment for infective endocarditis. Which of the following is the most likely medication causing this appearance?

• a) Flucloxacillin

• b) Gentamycin

• d) Penicillin

• d)    Vancomycin

Multiple Choice

5) The mosquito vector of this parasite in Sri Lanka is

• a) Aedes aegypti

• b) Anopheles culicifacies

• c) Culex quinquefasciatus

• d) Mansonia uniformis

Multiple Choice

6) What is the type of  injury seen in the cells indicated by the arrow?

• a) Irreversible cell injury

• b) Necrosis

• c) Apoptosis

• d) Necroptosis

• e) Hydropic change

Multiple Choice

7) Escherichia coli was isolated from a blood culture collected from a patient with pyelonephritis. The antibiotic susceptibility test plate is given below. What is likely the resistance mechanism showing in the plate.

• a)  D Zone

• b)   ESBL production

• c)  MRSA detection

• d)  Carbapenem resistance

Multiple Choice

8) Which of the following increase cholinergic neurotransmission?

• a) Atropine

• b) Tubocurarine

• c) Neostigmine

• d) Pralidoxime

Multiple Choice

9) This parasitic stage was isolated from a sample of sandy soil contaminated with dog faeces. What is the most likely disease condition caused by this parasite?

• a) Cutaneous larva migrans

• b) Dracunculiasis

• c) Larva currens

• d) Visceral larva migrans

Multiple Choice

10) This baby is having a tumour in the eye.

What is the most likely type of gene mutated in this tumour?

• a) Antiapoptoc gene

• b) DNA repair gene

• c) Oncogene

• d) Oncosuppressor gene

• e) Mismatch repair genes

Multiple Choice

11) A 5-year-old child presented with vesicular skin lesion on her hand. What is the most likely diagnosis?

• a)  Varicella infection

• b)   HSV infection

• c)  Mpox (Monkeypox)

• d)   Molluscum contagiosum

Multiple Choice

12) The following fixed dose combination is used in co-trimoxazole?

• a) Sulfamethoxazole and trimethoprim

• b) Trimethoprim and clavulanic acid

• c) Sulfamethoxazole and Clavulanic acid

• d) Clavulanic acid and metronidazole

Multiple Choice

13) A faecal survey was carried out among school children in Wattala for intestinal parasites. This was identified in a  direct faecal smear in saline;

What parasite species produces these eggs?

• a) Bertiella studeri

• b) Hymenolepis diminuta

• c) Hymenolepis nana

• d) Taenia solium

Multiple Choice

14) Squamous cell carcinoma of the genitalia in chimney sweepers was the first occupational cancer reported in history.

Who initially identified this link?

• a) James Paget

• b) Marie Curie

• c) Percival Pott

• d) Theodor Boveri

Multiple Choice

15) A 50-year-old man was diagnosed with sepsis following acute pyelonephritis. His blood culture grew a coliform spp, which was an ESBL producer. Which of the following is the best antibiotic choice for the management of this patient?

• a)  Co-amoxiclav

• b)   Ceftriaxone

• c)   Gentamycin

• d)  Meropenem

Multiple Choice

16) Which of the following cephalosporins can be administered orally

• a)     cefixime

• b)   Cefotaxime

• c)    Ceftazidime

• d)   Ceftriaxone

Multiple Choice

17) What is the natural habitat of this parasite in

 the human host?

• a ) Alveoli of lungs

• b) Bile ducts

• c) Blood vessels

• d) Liver parenchyma

Multiple Choice

18) This is a physician, anthropologist, politician and social reformer. But he is best known as the founder of the field of cellular pathology.Who is he?

• a) Carl Von Rokitansky

• b) Rudolph Virchow

• c) William Hewson

• d) Xavier Bichat

Multiple Choice

19) Leptospira spp isolated from Sri Lanka has shown no resistance to antibiotics. However,the minimum inhibitory concentration (MIC) for an antibiotic is rising. What is the antibiotic which shows increasing MIC by Leptospira spp?

• a)    Ceftriaxone

• b) Ciprofloxacin  

• c)   Doxycycline

• d) Penicillin

Multiple Choice

20) Above diagram shows dose-response curves that relate the dose of four drugs to the size of a particular response / therapeutic effect.

• a)    The pharmacologic potency of drug A is greater than that of drug B

• b) Drug A has a larger maximal efficacy than drug B

• c) Drugs A, C and D have different maximal efficacies

• d)   Drug D has a wider therapeutic index than drug C

Multiple Choice

21) This is a British doctor, who served in the British Indian Medical service and won the Nobel prize for discovering the mosquito stages of malaria parasites.  He is:

• a) Camillo Golgi

• b) Charles Louis Laveran

• c) Sir Patrick Manson

• d) Sir Ronald Ross

Multiple Choice

22) A mother and her baby presented to the well baby clinic with an itchy rash on hands and feet for one week duration.

Which of the following parasites is the most likely cause for their presentation?

• a)

• b)

• c)

• d)

Multiple Choice

23) Which of the following viral infections are best prevented by vaccination?

• a) Hepatitis C virus (HCV) infection

• b) Hepatitis D virus (HDV) infection

• c) Human immunodeficiency virus (HIV) infection

• d) Herpes simplex virus type-1 (HSV-1) infection

Multiple Choice

24) A drug is known to undergo extensive metabolism by a cytochrome P450 enzyme. Which of the

following is least likely to influence the clearance of that drug?

• a) Genetic polymorphisms

• b) Drug interactions

• c) Protein binding

• d) Hepatic blood flow

Multiple Choice

25) This space occupying lesion in the liver (arrow in A ) was aspirated under ultrasound guidance,  aspirate shown in B and organism (arrow in C ) was visualized by microscopy.

What is the diagnosis?

• a) Amoebic liver abscess

• b) Hydatid cyst of liver

• c ) Pyogenic liver abscess

• d) Fascioliasis

Multiple Choice

26) This is a section of a tumour
What is indicated by the arrows?

• a) Apoptosis

• b ) Abnormal mitosis

• c) Clumped chromatin

• d) Enlarged nucleoli

• e) Pyknosis

Multiple Choice

27) What is the most accurate statement regarding infectious prion proteins

• a) Present in normal human nervous tissue

• b) Degraded by protease

• c) elicit poor immune response

• d) effectively sterilized by autoclaving at 121 ⁰C for 15 mins

Multiple Choice

 28) A patient is prescribed a drug with a half-life of 6 hours. How long does it take for approximately 75% of the drug to be eliminated from the body?

• a) 3 hours

• b) 6 hours

• c) 9 hours

• d) 12 hours

Multiple Choice

29) This picture shows the a sequalae of a parasitic disease leading to blindness in African countries. What is the causative parasite?

• a ) Dirofilaria repens

• b ) Loa loa

• c ) Onchocerca volvulus

• d) Toxocara canis

Multiple Choice

30) What feature of a malignant tumour is shown in this photomicrograph?

• a) Vascular invasion

• b) Capsular invasion

• c) Liver Metastasis

• d) Perineural invasion

Multiple Choice

31) What is the most accurate statement regarding mumps

• a)   has three serotypes

• b) transmitted by airborne route

• c) Humans are the only natural hosts

• d)   MMR vaccine is safely given to HIV patients

Multiple Choice

32) What is the most likely mosquito to breed in this environment?

• a) Aedes spp.

• b) Anopheles spp.

• c ) Culex spp.

• d) Mansonia spp.

Multiple Choice

33) Which cell is predominantly seen in an acute inflammatory site?

• a)

• b)

• c)

• d)

Multiple Choice

34) Which of the following viral component is not used for diagnosis of HIV infection

• a) Viral RNA

• b) P24 antigen

• c) gp120 antigen

• d) Proviral DNA

• e) Anti-HIV antibody assay

Multiple Choice

35) The following parasitic stage was demonstrated in a peripheral blood smear from a 56-year-old lady presented with fever and headache, who recently returned from a pilgrimage to India.

What is the most appropriate treament?

• a) Chloroquine 25 mg/kg over 3 days + Primaquine 0.25 mg/kg/day for 14 days

• b) Chloroquine 25 mg/kg over 3 days + Primaquine 0.25 mg/kg/day for 7 days

• c) Chloroquine 25 mg/kg over 3 days + Primaquine 0.5 mg/kg for 7 days

• d) Coartem over  3 days + Primaquine 0.75 mg/kg single dose

Multiple Choice

36) What is the most likely mediator responsible for the redness in this patient’s toes?

• a) Histamine

• b) Tumour necrosis factor (TNF)

• c) Interleukin - 1 (IL-1)

• d) Prostaglandin

Multiple Choice

37) A 7-year-old boy is brought to the out-patient department with fever, sore throat and runny nose for 2 days. His 4-year-old younger brother who is pre-schooling had similar symptoms 3 days ago. His 1-year-old youngest sister is asymptomatic.Which of the following is the best practice of prescribing antimicrobials to this patient?

• a) Prescribe oral penicillin for treatment of pharyngitis

• b) Symptomatic treatment without antibiotics

• c) Prescribe amoxicillin to prevent a possible 2ry bacterial pneumonia

• d) Prescribe amoxicillin to prevent transmission of infection to the youngest sister

Multiple Choice

38) Which of the following practice would prevent acquisition of healthcare associated hepatitis B infection?

• a) Recapping of used needles by using one hand (scoop method)

• b) Using bottles of intravenous solution as a common source of supply between patient

• c) Directly discarding used needles to a sharps bin

• d) Cleaning skin of patient with 70% alcohol before blood drawing

Multiple Choice

39) Select the most likely microscopic appearance of a granuloma in tuberculosis

• a)

• b)

• c)

Multiple Choice

40) A 50-year old man was admitted with fever, productive cough and difficulty in breathing for 3 days. He had neutrophil leukocytosis and high CRP. His chest X ray showed a left lobar pneumonia. His blood culture grew the organism shown. 

What feature in the history would be most suggestive of the exposure risk to this infection?

• a)    Recent travel to an African country

• b)  Recent exposure to muddy surface water

• c)   Overcrowding

• d)   Close contact with a known infected patient