Lymphoproliferative Disorders Lesson

Multiple Choice

Which organs are commonly affected by neoplastic lesions of the lymphoid system as described in the definition?

• Bone marrow, blood, and lymph nodes

• Liver, kidney, and pancreas

• Heart, lungs, and brain

• Skin, muscle, and bone

Multiple Choice

Based on the diagram, which cell types can give rise to lymphomas and multiple myeloma?

• B lymphocytes and plasma cells

• Red blood cells and platelets

• Granulocytes and eosinophils

• Myeloblasts and neutrophils

Multiple Select

Which of the following are classified as mature malignant lymphoproliferative disorders?

• Lymphoma

• Lymphoid leukemia

• ALL

• Both Lymphoma and Lymphoid leukemia

Fill in the Blanks

Fill in the blank: Hodgkin’s lymphoma is a type of

.

Multiple Choice

Which of the following is NOT a common sign or symptom of a myeloproliferative disease?

• Persistent fatigue

• Itchy skin

• High blood pressure

• Painless swelling in lymph nodes

Multiple Select

Which of the following are common findings in the examination of a patient with acute leukaemia?

• Petechial rash

• Splenomegaly

• Hypertension

• Hepatomegaly

Multiple Choice

Which symptom is more likely to be present in ALL than in AML?

• Lymphadenopathy

• Pallor

• Fatigue

• Easy bruising

Multiple Choice

Which chromosome abnormality is most commonly associated with Chronic Myeloid Leukaemia?

• Philadelphia chromosome

• BRCA1

• Chromosome 6 deletion

• JAK2 mutation

Fill in the Blanks

The characteristic cell seen in Hodgkin Lymphoma is the

cell.

Multiple Select

Which of the following are considered risk factors for Hodgkin Lymphoma?

• HIV

• Epstein-Barr virus

• Autoimmune conditions

• Smoking

Multiple Choice

Which of the following is the recommended treatment for stage one and two A Hodgkin lymphoma?

• Radiotherapy plus short course of chemotherapy

• Longer course of ABVD chemotherapy

• High dose chemo with autologous stem cell transplantation

• Surgery

Multiple Choice

All of the following medications may be used as treatment for Multiple Myeloma except:

• Lenalidomide

• Dexamethasone

• Bortezomib

• Rituximab

Multiple Choice

A patient presents with a painless, rubbery lymph node in the cervical chain that is fixed and solid to touch. What is the most likely diagnosis?

• Hodgkin Lymphoma

• Acute Lymphoblastic Leukaemia

• Chronic Myeloid Leukaemia

• Non-Hodgkin Lymphoma

Multiple Choice

Which of the following is a core presentation associated with lymphoproliferative disorders?

• Organomegaly

• Hypertension

• Diabetes

• Jaundice

Multiple Choice

Which Lymphoproliferative Disorder presents with osteolytic bone lesions?

• Multiple Myeloma

• Waldenstrom Macroglobulinaemia

• MGUS

• Hodgkins Lymphoma