Q2W4: Fri 11/7 - Types of Mutations Notes

Happy Friday! 11/7

Q2W4

BW Fri 11/7

Go to PG 37 (Unit 3 IDEAS Chart)

Types of Mutations Notes (PG 46)

Use the instructions on the following slides to complete PG 46 in your NB!

Types of Mutations Notes (PG 46)

Now do Mutated DNA Sequence 2 and 3!

Types of Mutations Notes (PG 46)

Use the text to answer 1-3!

Types of Mutations Notes (PG 46)

First transcribe! DNA - RNA

Then translate! RNA - Protein! (use codon chart)

Now transcribe/translate mutated sequence!

Answer reflection!

Multiple Choice

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

• Substitution

• Deletion

• Insertion

• Frameshift

Multiple Choice

Which of the following would result in a frameshift mutation?

• Insertions only

• Substitution only

• Deletion only

• Insertions and Deletions

Multiple Choice

DNA molecule segment is : TTACGCAAG

The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.

• Substitution

• Deletion

• Insertion

• Inversion

Multiple Choice

A mutation is defined as:

• A change in the cell's structure

• Anything that changes in an embryo

• Any change in the physical features of a human

• A change in the DNA sequence

Multiple Choice

ATTTGAGCC- Original

ATTGAGCC - Mutated

The example above is an example of a

• Insertion- Frameshift

• Deletion- Substitution

• Deletion -Frameshift

• All of the above

Multiple Choice

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

• Substitution

• Deletion

• Insertion

• Frameshift

Multiple Choice

Why are insertion and deletion (frameshift) mutations so harmful?

• They change all of the codons from the mutation on down the line, which changes the amino acid sequence

• They insert things that an organism doesn't need.

• They often delete things that organisms need.

• Insertion and deletions are not any more harmful than substitution mutations.

Multiple Choice

Identify the DELETION mutation form the following:

ATG CCA AAT

• ATG TCA AAT

• ATG CCT AAA T

• ATC CA AT

• ATG CCA AAT

Multiple Choice

Which mutation will cause translation to stop?

• Mutations 1 and 3 only

• Mutation 1 only

• Mutation 2 only

• Muations 1, 2, 3

Multiple Choice

Which type of mutation does the model demonstrate?

• Deletion

• Substitution

• Insertion

• Translocation