Mutations

Any change in the sequence of DNA is...

• transgenic shift
• Single Genotype
• Monohybrid Trait
• Mutation

Tags

NGSS.HS-LS3-2

What mutation has occurred here? 
T-G-A-C-C-A
T-G-A-G-C-A

• Substitution
• Deletion
• Insertion
• Frameshift 

Tags

NGSS.HS-LS3-2

Normal-
AGA-TTC-ATA-GCG
Mutant-
AGA-TTC-AAT-AGC-G

• deletion frameshift
• insertion frameshift
• substitution
• nonsense

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

Are all mutations bad?

• Yes
• No

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

Why are insertion and deletion (frameshift) mutations so harmful?

• They change all of the codons from the mutation on down the line, which changes the amino acid sequence
• They insert things that an organism doesn't need.
• They often delete things that organisms need.
• Insertion and deletions are not any more harmful than substitution mutations.

Tags

NGSS.HS-LS3-2

Why is the order of amino acids so important?

• The order of amino acids dictates what shape the protein will fold into.
• It is not important. The protein folding chamber will force the protein to fold into the correct shape.

Tags

NGSS.HS-LS1-1

What type of chromosomal mutation is this?

• Inversion

• Translocation

• Deletion

• Duplication

What kind of mutation would have the greatest effect on the protein?

• Missense- 1 amino is changed

• Silent- no amino acids are changed

• Frameshift- all amino acids after the mutation are changed

Tags

NGSS.HS-LS3-2

UV light from the sun is an example of a ___________ because it can cause mutations.

• Mutagen

• Mutation

• Meiosis

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

Would a mutation in the DNA of a skin cell be passed on to an organism's offspring?

• Yes, because any change to the DNA is passed on to the offspring

• Maybe. Sex cells only use half of the body's genetic code. It might get the copy of a gene that wasn't mutated.

• No. Only mutations that occur in the gametes (sex cells) are passed on to the offspring

• Without knowing the animal, it would be hard to tell whether or not the mutation would be passed on.

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2