Trypanosoma cruzi

Trypanosoma Cruzi, causes what disease?

• African sleeper sickness

• Chagas disease

Transmitted to humans by?

• Ticks

• Tetse fly

• Triatomine bugs, "kisser bugs"

Intermediate host, and not final host?

• Humans

• Bugs

Where does it divide?

• Reticuloendothelial and other tissues

• Blood

Might invade?

• Bone Marrow

• Nervous system

Acute phase is often asymptomatic. But can present with manifestations that include?

• Myocarditis

• Keratitis

Symptomatic form of this disease manifest shortly after the acute?

• Yes, almost immediately

• No, the acute phase can be prolonged to years and even over decades

How does the host get infected by this parasite?

• Kisser bug--> Blood meal--> "Bajser"/"Slipper en snickers" near the bite wound--> Feces contain parasite(Trypomastigote)

• Blood meal from "bed bugs", salivary glands contain Trypomastigote

How does it survive?

• "Kisser" bugs eats human feces

• "Kisser" bugs gets infected by blood meal from infected host

What is the diff. of the behaviorism of bloodstream mastiogote of Tryposoma Cruzi and Tryposoma Gambiense?

• Binary fission in blood, multiplies

• Does not mulitply in blood, only when trypomastigote transform into amasiogote in cell tissues