
Cell Differentiation
Quiz
•
Biology
•
9th - 12th Grade
•
Practice Problem
•
Medium
+4
Standards-aligned
Susan Campeau
Used 812+ times
FREE Resource
About this resource
This quiz focuses on cell differentiation and specialization, which is a fundamental concept in high school biology appropriate for grades 9-12. The questions assess students' understanding of how genetically identical cells develop into specialized cell types with distinct structures and functions. Students need to grasp that while all somatic cells contain the same DNA, different genes are expressed in different cell types through regulatory mechanisms that turn specific genes on or off. The quiz evaluates comprehension of key processes including fertilization, the role of stem cells as precursors to specialized cells, and how chemical signals from the organism or environment control gene expression patterns. Students must understand that cell differentiation is driven by selective gene activation rather than changes to the actual DNA sequence, and that this specialization ultimately serves the organism's need to maintain homeostasis through diverse cellular functions. Created by Susan Campeau, a Biology teacher in the United States who teaches grades 9-12. This quiz serves as an excellent formative assessment tool to gauge student understanding of cellular differentiation before moving into more advanced topics in developmental biology or genetics. Teachers can use this as a warm-up activity to activate prior knowledge, as guided practice during instruction, or as homework to reinforce learning after lessons on cell specialization. The quiz effectively supports review sessions before unit tests and helps identify misconceptions about gene expression and cellular development. This assessment aligns with Next Generation Science Standards HS-LS1-4, which requires students to use representations to model how DNA provides instructions for synthesizing proteins that determine traits, and supports understanding of how cells become specialized through differential gene expression patterns.
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10 questions
Show all answers
1.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
All our cells, except sex cells like eggs or sperm, have ___________ DNA
Tags
NGSS.MS-LS3-2
2.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
The diagram shows the process of cell specialization from a single stem cell. Which of the following statements is true about the process of specialization.
Tags
NGSS.HS-LS1-4
3.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
In what way is the DNA of a nerve cell different from the DNA of a muscle cell?
Tags
NGSS.MS-LS3-1
4.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
When one sperm cell combines with one egg cell.
Tags
NGSS.HS-LS3-2
NGSS.HS-LS4-2
5.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
How do stem cells know what type of cells to differentiate into?
Tags
NGSS.HS-LS1-4
6.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
What is cell specialization or differentiation?
Tags
NGSS.HS-LS1-4
7.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
What is one goal of cellular differentiation/specialization?
Tags
NGSS.HS-LS1-3
NGSS.HS-LS1-4
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