
Cell Signaling
Biology
9th - 12th Grade
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This quiz focuses on cellular communication processes, specifically the mechanisms of cell signaling and signal transduction pathways. Designed for high school biology students at the 9th through 12th grade level, these questions assess understanding of fundamental concepts including ligands, receptors, second messengers, and the three-step signal transduction process of reception, transduction, and response. Students need to comprehend how signal molecules interact with target cells through specific receptor proteins, understand the role of G proteins and phosphorylation cascades in amplifying cellular messages, and recognize how second messengers relay signals throughout the cytoplasm. The quiz requires students to distinguish between different types of membrane proteins, explain the function of ligand-gated ion channels, and analyze diagrams showing receptor-ligand interactions. Mastery of these concepts builds on foundational knowledge of cell membrane structure and protein function while preparing students for advanced topics in molecular biology and biochemistry. This quiz was created by a classroom teacher who designed it for students studying cell signaling in grades 9-12. The assessment serves multiple instructional purposes, functioning effectively as a formative assessment tool to gauge student understanding before moving to more complex topics like hormonal regulation or neural communication. Teachers can deploy this quiz as a warm-up activity to activate prior knowledge about membrane proteins and cellular communication, or assign it as homework following lessons on signal transduction mechanisms. The varied question formats, including diagram analysis and conceptual applications, make it valuable for review sessions before unit exams or as guided practice during collaborative learning activities. This assessment aligns with NGSS standards HS-LS1-3 (cellular basis of inheritance and variation) and supports Common Core literacy standards in science by requiring students to analyze scientific information and apply biological concepts to specific scenarios.
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10 questions
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1.
MULTIPLE CHOICE QUESTION
1 min • 12 pts
A signal molecule that binds to a plasma-membrane protein is a
2.
MULTIPLE CHOICE QUESTION
1 min • 12 pts
What do second messengers do?
3.
MULTIPLE CHOICE QUESTION
1 min • 12 pts
What determines whether a cell is a target cell for a particular signal molecule?
4.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
In cell signaling, how is the flow of specific ions
regulated?
Opening and closing of ligand-gated channels
Transduction
Cytoskeleton rearrangement
Endocytosis
5.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
What is a G protein?
A protein on the cytoplasmic side of the a membrane that becomes activated by a receptor protein
A specific type of membrane receptor protein
A membrane bound enzyme that converts ATP to cAMP
A tyrosine kinase relay protein
6.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
Many signal transduction pathways use second messengers to:
transport a signal through the lipid bilayer portion of the plasma membrane.
relay a signal from the outside to the inside of the cell.
relay the message from the inside of the membrane throughout the cytoplasm.
amplify the message by phosphorylating proteins.
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
The 3 steps of signal transduction in order are
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