AP Bio: Cell Cycle Regulation/ Cancer

Which phrase best describes a common characteristic of all cancers?

• absence of cyclins
• damaged DNA
• uncontrolled cell growth
• inherited from parents

Tags

NGSS.MS-LS3-1

What is the role of protein kinases?

• remove phosphate groups to deactivate enzymes

• trigger apoptosis

• add phosphate groups and energy to activate enzymes

• stop the cell cycle

Which of these may be assessed by various proteins during a "checkpoint"?

• Ensure that all chromosomes have lined up in the center of the cell before sister chromatids separate

• Ensure that spindle fibers have attached to all centromeres before cell division

• Ensure that DNA has been replicated properly

• All of them

Tags

NGSS.HS-LS1-4

Which description is true about cell cycle regulation?

• Changing concentrations of Cdk result in binding to cyclin
• Changing concentrations of cyclin result in binding to Cdk
• MPF complex formation decreases with increased Cdk levels
• MPF complex formation decreases with increased cyclin levels

In which stage of the cell cycle are cells most susceptible (likely to experience) to mutations?

• G1

• S

• G2

• G0

Tags

NGSS.HS-LS3-2

Which of the following correctly describes cells that are in the G₀ phase?

• Mature nerve and muscle cells are unable to divide and are permanently in G₀.

• Many cells enter G₀ when they reach the checkpoint during the M phase.

• Cells in G₀ are growing and preparing for cell division.

• DNA replication occurs during G₀.

The graph represents the amount of DNA in the nucleus of each cell during the cell cycle.
Which region represents the G2 phase?

• I
• II
• III
• IV

Tags

NGSS.HS-LS1-4

How does the concentration of cyclin dependent kinases (Cdk) change as the cell proceeds through the cell cycle?

• Cdk concentration remains constant.
• Cdk concentration increases during interphase and decreases during mitosis.
• Cdk concentration decreases during interphase and increases during mitosis.
• Cdk concentration correlates directly with MPF concentration.

Tags

NGSS.HS-LS1-4

How does the concentration of cyclin change as a cell goes through the cell cycle?

• Cyclin concentration remains constant.
• Cyclin concentration increases during interphase and decreases during mitosis.
• Cyclin concentration decreases during interphase and increases during mitosis.
• Cyclin concentration is inversely related to MPF concentrations.

Tags

NGSS.HS-LS1-4

Once a cell completes mitosis, what happens to MPF? 

• It is completely degraded
• it is exported from the cell
• the cyclin component of MPF is degraded
• the Cdk component of MPF is degraded

Tags

NGSS.HS-LS1-4