Intracellular accumulation &calcification_DrKishore

A 44-year-old man has had increasing arthritis pain, swelling of the feet, and reduced exercise tolerance over the past 3 years. Laboratory studies include serum glucose of 201 mg/ dL, and ferritin of 893 ng/ mL. He undergoes a liver biopsy; the microscopic appearance of a biopsy specimen stained with H& E (right panel) and Prussian blue (left panel) is shown in the figure. Identify the substance that accumulated in the hepatocytes in the patient.

• Melanin

• Haemosiderin ( Iron)

• Glycogen

• Lipid

Identify the pigment shown in the histologic section from heart in an aged person died at the age of 87.

• Hemosiderin

• Alpha-1 Antitrypsin

• Lipofuscin

• Glycogen

Which special stain is used here to identify Haemosiderin in liver biopsy ?

• Prussian blue

• Alcian blue

• New Methelene blue

• Luxol fast blue

Which of the following endogenous pigment is also known as “ wear-and-tear pigment “ and acts as telltale sign of free radical injury ?

• Haemosiderin

• GCarbon

• Lipofuscin

• Melanin

Which of the following type of calcification is seen in areas of necrosis in presence of normal serum calcium level?

• Dystrophic calcification

• Metastatic calcification