Oxygen Dissociation Curve (2)

With reference to the graph, which of the statements is true?

• The blue arrow labelled A represents a shift to the left

• The purple arrow labelled B represents a shift to the left

• The red line that is not labelled represent the percentage saturation of oxygen with haemoglobin at different partial pressure of oxygen

Which of the following conditions will cause A to happen?

• increase in partial pressure of carbon dioxide

• decrease in partial pressure of carbon dioxide

• increase in pH

• decrease in temperature

What will shift A represent?

• an increase in affinity of haemoglobin for oxygen

• an increase in the affinity of haemoglobin for hydrogen carbonate ions

• a decrease in the affinity of haemoglobin for oxygen

• a decrease in the affinity of oxygen for haemoglobin

What CANNOT cause shift A to happen?

• increase in partial pressure of carbon monoxide

• increase in hydrogen ion concentration

• increase in temperature

• increase in levels of 2,3-DPG

The Bohr effect causes …………………………..

• shift B to happen

• shift A to happen

• affinity of haemoglobin for oxygen to increase

• affinity of haemoglobin for carbon dioxide to increase

With reference to the graph, which of the following statement is true?

• more oxygen is released when blood moves from a resting tissue to a contracting skeletal muscle, compared to what is released when blood moves from a resting tissue to the lungs?

• more oxygen is released when blood moves from a resting tissue to a contracting skeletal muscle, compared to what is released when blood moves from the lungs to a resting tissue?

• deoxygenated blood is blood that has lost all it's oxygen

• oxygenated blood is blood that has reached at least 90% saturation

The P₅₀ is defined as the oxygen tension or partial pressure at which hemoglobin is 50% saturated. What will increased pH do to P₅₀

• It will increase P₅₀

• It will decrease P₅₀

• It will stabilize P₅₀

• It will double P₅₀

The P₅₀ is defined as the oxygen tension or partial pressure at which hemoglobin is 50% saturated. Which of the following statements is therefore true?

• Fetal haemoglobin will have higher P₅₀ compared to adult haemoglobin

• High P₅₀ indicates high affinity for oxygen

• Myoglobin has lower P₅₀ compared to adult haemoglobin

• High P₅₀ indicates low affinity for oxygen

What is the correct labels for the graphs

• 1 represents pH of 7,

  2 represents pH of 7.5,

  3 represents pH of 8

• 1 represents pH of 5,

  2 represents pH of 5.5,

  3 represents pH of 11

• 1 represents pH of 8.5,

  2 represents pH of 8,

  3 represents pH of 7.5

The P₅₀ is defined as the oxygen tension or partial pressure at which hemoglobin is 50% saturated. Which graph represents an haemoglobin with the LOWEST P₅₀

• Graph 1

• Graph 2

• Graph 3