Bioinformatics - FASTA

Which of the following is not correct about FASTA?

• a) Its stands for FAST ALL

• b) It was in fact the first database similarity search tool developed, preceding the development of BLAST

• c) FASTA uses a ‘hashing’ strategy to find matches for a short stretch of identical residues with a length of k

• d) The string of residues is known as blocks

The first step in FASTA alignment id to arrange the sequences in matrices’ rows and columns in order to be analyzed.

• a) True

• b) False

The positional difference for each word between the two sequences is obtained by ________ the position of the ______ sequence from that of the _______ sequence and is expressed as the offset.

• a) subtracting, second, first

• b) adding, second, first

• c) adding, first, second

• d) subtracting, first, second

The second step in FASTA is to narrow down the high similarity regions between the two sequences.

• a) True

• b) False

In FASTA, neighboring high-scoring segments along the same diagonal are selected and joined to form a single alignment.

• a) True

• b) False

The last step is to perform a statistical evaluation of the final alignment as in BLAST, which produces the E-value.

• a) True

• b) False

.In Dynamic programming method, what is the score for number of gaps?

• (a) -1

• (b) +1

• (c) - 2

• (d) +2

FASTA is a ------ method

• (a) Number based

• (b) Word based

• (c) Both

• (d) None

e -value is

• (a) End value

• (b) electronic value

• (c) expected value

• (d) extreme value

The initiation of FASTA format has ____ symbol.

• a) >

• b) <

• c) /

• d) *