Rabies Virus

Family of rabies virus :

• Retrovirodae

• Lyssavirus

• Enterovirus

• Rhabdoviridae

Genus of rabies virus :

• Retrovirodae

• Lyssavirus

• Enterovirus

• Rhabdoviridae

General structure of rabies virus :

• Enveloped, helical capsid, (-) ssRNA, non-segmented

• Enveloped, helical capsid, (+)ssRNA, non-segmented

• Non-enveloped, icosahedral capsid, dsDNA, non-segmented

• Enveloped, helical capsid, ssDNA, segmented

Genome of rabies virus

• contains 2 genes : Nucleoprotein (N), phosphoprotein (NS)

• contains 3 genes : Nucleoprotein (N), phosphoprotein (NS), Matrix (M)

• contains 4 genes : Nucleoprotein (N), phosphoprotein (NS), matrix (M), glycoprotein (G)

• contains 5 genes : Nucleoprotein (N), phosphoprotein (NS), matrix (M), glycoprotein (G), polymerase (L)

Rabies can infect :

• Lime-blooded animals

• Arthropods

• Amphibians

• Crustaceans

Transmission of rabies virus :

• Bite or scratch from a rabid animal or pet

• Projection of infected saliva into conjunctiva, cornea transplant

• Inhalation of infected aerosol

• Eating the same plate and spoon

• Talking to each other on phone

After being bitten by a rabies animal, rabid virus replicates primarily in

• muscles

• spinal cord

• dorsal ganglia

• brain

After the replication in muscles, rabies virus travels within axons in peripheral nerves to infect :

• muscles

• spinal cord

• dorsal ganglia

• brain

• spinal cord, dorsal ganglia, then ascends to the brain

After infecting the brain, rabies virus has a centrifugal spread along nerves to

• salivary glands

• skin

• eyes

• All are correct.

Rabies virus incubates in racoon's body for approximately

• 7 days

• 1 week

• 3 - 12 weeks

• 10 - 20 weeks