Cell Cycle and Checkpoints

Which molecules act as gatekeepers for each checkpoint of the cell cycle?

• p53 gene

• cyclins and cycline-dependent kinases

• thyroid hormones

What is the purpose the the cell cycle checkpoints?

• To repair damaged cells before they enter cell division.

• To remove damaged cells from an organism.

How many cell cycle checkpoints are there?

• 1

• 2

• 3

• 4

What is the first checkpoint of the cell cycle?

• Mitosis checkpoint

• G₁ checkpoint

• G₂ checkpoint

When is apoptosis initiated?

• When DNA damage is repaired.

• When cells are removed from the cell cycle.

• When DNA damage cannot be repaired.

Uncontrolled cell division is stopped by...

• tumor suppressor genes
• oncogenes

Tags

NGSS.HS-LS1-4

Which is an example of a tumor suppressor gene?

• apoptosis
• proto-oncogenes
• p53
• oncogenes

Tags

NGSS.HS-LS3-2

p53 activates which of the following?

• Tumor suppressor genes
• cell cycle
• DNA repair proteins
• uncontrolled cell division

Which of the following statements is true?

• Proto-oncogenes cause a loss of control of the cell cycle
• the products of oncogenes may inhibit the cell cycle
• tumor-suppressor-gene products inhibit the cell cycle
• a mutation in a proto-oncogene may convert it into a tumor suppresor gene

Tags

NGSS.HS-LS1-4

This is the cell cycle checkpoint that makes sure environmental conditions are ideal for cell survival.

• G1 Checkpoint
• G2 Checkpoint
• M Checkpoint
• I Checkpoint