DNA History and Replication

Erwin Chargaff's rule of base pairing states that:

• adenine pairs with thymine and guanine pairs with cytosine

• adenine pairs with guanine and thymine pairs with cytosine

• purines pair with pyrimidines

• pyrimidines pair only with pyrimidines

Rosanlind Franklin's x-ray diffraction image of her study of DNA was noticed by Watson and Crick and led them to model what they thought the shape and structure of DNA was. What was that shape?

• the double helix

• the single strand

• the sugar and phosphate

• the four nitrogen bases

Thymine, adenine, guanine, cytosine, and uracil are classified as:

• sugars

• codons

• nitrogen bases

• nucleotides

What is the backbone of this DNA molecule made of?

• sugars

• nitrogen bases

• sugar and phosphate

• sugar and nitrogen bases

What type of bonds hold together nitrogen bases?

• water bonds

• covalent bonds

• peptide bonds

• hydrogen bonds

Using the bases on the template strand of DNA, what are the new complimentary bases for replication? Template: AGTCA

• AGTCA

• TCAGT

• UCAGU

• TCUGT

What enzyme unzips the DNA strands to allow replication to occur?

• polymerase

• ligase

• helicase

• primase

All of the following are differences between DNA and RNA except

• they are both nucleic acids

• the shape of the strand

• the type of sugar

• the specific nitrogen bases

Which of the following is not part of a molecule of DNA?

• ribose sugar

• deoxyribose sugar

• nitrogen base

• phosphate group

A strand of DNA has these bases: AGCCATGTATAC. What is the complementary DNA strand?

• UCGCUACAUAUG

• TGCCTAGATATAC

• TCGGTACATATG

• ACGGATCTATAG