MIDTERM PCOL JK

Rate limiting step of catecholamine synthesis

• tyrosine hydroxylase
• DOPA decarboxylase
• Dopamine B-hydroxylase
• Phenyethanolamine N methyltransferase

Enzyme that converts DOPA to dopamine

• tyrosine hydroxylase
• DOPA decarboxylase
• Dopamine B-hydroxylase
• Phenyethanolamine N methyltransferase

enzyme that converts NE to epinephrine from the adrenal medula

• tyrosine hydroxylase
• DOPA decarboxylase
• Dopamine B-hydroxylase
• Phenyethanolamine N methyltransferase

enzyme that converts dopamine to NE

• tyrosine hydroxylase
• DOPA decarboxylase
• Dopamine B-hydroxylase
• Phenyethanolamine N methyltransferase

final metabolite of dopamine

• 3-methyl-4 hydroxymandelic acid
• vanilyl mandelic acid
• homovanillic acid
• 4-methoxy-3-hydroxy mandelic acid

historical use of Isoproterenol

• heart failure
• stroke
• bronchial asthma
• septic shock

DOC for septic shock

• epinephrine
• NE
• dopamine
• dobutamine

DOC for anaphylactic shock

• epinephrine
• NE
• dopamine
• dobutamine

DOC for cardiogenic shock with renal insufficiency

• epinephrine
• NE
• dopamine
• dobutamine

DOC for cardiogenic shock

• epinephrine
• NE
• dopamine
• dobutamine