
BIOC2: Week 9 - Purines
Quiz
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Science
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University
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Medium
Ashley McClelland
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5 questions
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1.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
What is the required form of folate for purine synthesis?
DHF
N-10-formyl THF
N-5-N-10-methylene THF
THF
2.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
Where does the sugar in synthesized nucleic acids come from?
glucose directly from circulation
ribose from PPP
diet
3.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
SCID is caused by a deficiency of which enzyme?
ADA
PRPP
HGPRT
4.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
A 2 year old male patient presents with intellectual disability, hyperuricemia, chorea (involuntary jerking movements), aggression, and compulsive lip and finger biting. Which reaction is compromised?
IMP + aspartate --> adenylosuccinate
Adenine + PRPP --> AMP
xanthine --> uric acid
Guanine + PRPP --> GMP
5.
MULTIPLE CHOICE QUESTION
2 mins • 1 pt
After missing a few feedings, a newborn becomes quite lethargic, and the parents rush the child to the emergency department. Blood analysis indicates elevated levels of lactate and uric acid and significantly decreased levels of glucose. After stabilizing the child with glucose infusions, a glucagon challenge is given to the infant, and blood glucose levels do not increase.
The accumulation of which metabolite in the liver is most responsible for the elevated uric acid seen in the circulation?
glucose
lactate
ribose-5-P
thymidine
acetoacetate
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