Formative assessment 1

1. The hallmark of acute inflammation is

• Increased blood flow

• Vascular stasis

• Increased vascular permeability

• Rubor, calor, dolor, tumor

Which cause pain in acute inflammation

• C3a

• C5a

• LTB4

• Bradykinin

A preformed mediator of inflammation is

• Prostaglandin

• Histamine

• Leucotriene

• Nitric oxide

Which of the following is not a common site for metastatic calcification?

• Kidney

• Gastric mucosa

• lung

• Parathyroid

Which is the most common mechanism of vascular leakage in acute inflammation-

• Endothelial cell contraction

• Junctional retraction

• Direct injury

• Leukocyte-dependent leakage

The first vascular response to injury is

• slowing of the circulation

• venular dilatation

• recruitment of the vascular beds

• capillary enlargement

Which of the following chemical mediators are involved in giant cell granulomatous inflammation

• Complement C5a

• Interferon γ

• Bradykinin

• Nitric oxide

Which type of amyloid is seen in chronic diseases-

• A beta2 microglobulin

• SAA type

• AL type

• ATTR

Epithelioid cell granulomas are composed of

• Neutrophils, fibroblasts, macrophages

• Lymphocytes, activated macrophages, fibroblasts

• Neutrophils, lymphocytes, epithelioid cells

• Epithelioid cells, plasma cells, mast cells

Leukocyte extravasation occurs in the following order

• Activation, rolling, transmigration, adhesion

• Rolling, activation, adhesion, immigration

• Adhesion, rolling, activation, transmigration

• Rolling, activation, adhesion, transmigration