Harvard Immunology Lecture Part 1

Which of the following is disease causing?

• Antigen

• Antibody

• Pathogen

• NK Cells

After a virus has entered and invaded epithelial cells in the lungs, replicate and spread this _____ immunity kicks in

• Adaptive

• Innate

• Antibodies

• Antibiotics

If a virus is too tough for the innate immune response, ____ immunity steps in but takes longer to "rev up".

• Innate

• Adaptive

• Neutrophils

• Antigen

The innate immune system is made up of ...

• Barrier Tissues

• Cells

• Molecules

• Antibodies

Barrier tissues include:

• Mucus at mucosal barriers

• Keratin on the skin

• Tight junctions between epithelial cells

• Pathogens

These leukocytes (WBCs) make up the innate immune system

• Help T-cells

• Neutrophils

• Macrophage

• Plasma B-cells

Once a pathogen is recognized, the innate immune cells will do which of the following?

• Phagocytosis

• Create antibodies

• Secrete cytokines and chemokines

• Form memory B-cells

NK (natural killer) cells detect and destroy virally infected cells by releasing ...

• Perforin

• Chemokines

• Granzymes

• Cytotoxic T-cells

Cytokines, chemokines, histamine are ____ which increase the rate of blood flow for faster immune response

• pro-lysis

• pro-inflammatory

• pro-teins

• pro-fitable

During an innate immune response to microbes pro-inflammatory molecules become "leaky" which means what ...

• Endothelial cells are being broken down causing vaso-leaking

• Loose connections between cells allow movement of fluid to tissues

• Breakdown in the first line of defense

• Barriers are not effective within the respiratory wall lining