Medicinal Chemistry

Name the linkage (or) bridge present in the structure of Artemisinin?

• Ester

• Peroxide

• Epoxide

• Glycosidic linkage

Pyrimethamine has the following IUPAC name:

• 2, 4-diamino-6-ethyl-5-(p-chlorophenyl) pyrimidine

• 2, 4-diamino-6-ethyl-5-(p-chlorophenyl) pyridine

• 2, 4-diamino-6-ethyl-5-(m-chlorophenyl) pyrimidine

• 2, 4-diamino-6-ethyl-5-(o-chlorophenyl) pyrimidine

Isoniazid inhibits the mycolic acid synthesis by acting on which enzyme ?

• DNA dependent RNA Polymerase

• DNA gyrase

• Mycolase synthatase

• RNA polymerase

1. At which position carboxylic acid functional group is present in fluoro quinolones?

• 2

• 5

• 4

• 3

Iodoxuridine chemically is -----------

• 2’-Deoxy-5-iodoxuridine

• 3’-Deoxy-5-iodoxuridine

• 2’-oxy-5-iodoxuridine

• 3’-oxy-5-iodoxuridine

Which element is present in the Foscarnet structure?

• Ferrous

• Fluorine

• Phosphorous

• Sulphur

Which nitro imidazole derivative has morpholino moiety?

• Tinidazole

• Ornidazole

• Timorazole

• Metronidazole

IUPAC name for metronidazole is

• 2-(2-methyl-5-nitro-1H-imidazol-1-yl)- methanol

• 2-(2-methyl-5-nitro-1H-imidazol-1-yl)- ethanol

• 2-(2-nitro-5-methyl-1H-imidazol-1-yl)- methanol

• 2-(2-nitro-5-methyl-1H-imidazol-1-yl)- ethanol

The raw material used for the synthesis of diethyl carbamazine is

• Toulene

• N- methyl Piperazine

• 3,4,5 – trimethoxy benzaldehyde

• N- methyl Pyridine

Heterocyclic system present in Diethyl carbamazine is

• Piperazine

• Piperidine

• Pyrrolidine

• Pyridine