Intro to apoptosis

Synapsis and crossing over occur only during...

• Prophase I of Mitosis

• Prophase I of Meiosis

• Prophase II of Meiosis

• Metaphase I of Meiosis

During Meiosis, two cellular divisions occur, along with two rounds of replication

• True

• False

The end result of Meiosis produces...

• 2 diploid cells

• 2 haploid cells

• 4 diploid cells

• 4 haploid cells

Apoptosis involves orderly fragmentation of the nucleus, the chromatin and results in blebbing

• True

• False

Which apoptotic pathway involves the Fas ligand interaction with the Fas receptor?

• Intrinsic apoptotic pathway

• Extrinsic apoptotic pathway

• None of the above

The apoptosome activates upon the release of what?

• Caspase 9

• Caspase 8

• Cytochrome c

• Apaf-1

Caspase 8 cleaves more caspases and brings destruction in the extrinsic apoptotic pathway

• True

• False

Smac/Diablo inhibits IAPs (Inhibitors of apoptosis)

• True

• False

Both increased cell division and decreased apoptosis lead to the development of?

Benign tumors metastasize

• True

• False