HUS2-23&24 Cells of the nervous system - neurons and glia & Injury & repair of the nervous system

Which of the following correctly matches the names of glial cells and their respective functions?

• Microglia: secrete hydrogen peroxide for extracellular direct damage

• Ependymal cells: secrete growth factors for neuronal growth and activity

• Astrocyte: phagocytose degenerating neuronal debris

• Oligodendrocyte: generate and maintain myelin sheath in PNS

• Satellite cells: undergo gliosis after CNS injury

Which of the following conditions would disrupt the function of blood-brain barrier?

• ischaemia

• hypertensive encephalopathy

• status epilepticus

• neoplastic lesions

• hyperkalemia

Which of the following about neurons is incorrect?

• Chromatolysis occurs after axonotmesis.

• Chromatolysis refers to breakdown of Nissl bodies.

• Nissl bodies functions as axonal transport.

• Nissl bodies resembles the function of rough ER.

• Neurofilaments as cytoskeleton provide structural support for axon.

PNS damage can have good regeneration and functional recovery while CNS has limited regeneration and functional recovery.

• True

• False

Which of the following promote the recovery of nerve after injury?

• Schwann cells

• Neurotrophic factors

• Myelin

• Astrocytes

• Microglia

Which of the following inhibit recovery of nervous system?

• Oligodendrocytes

• Nogo

• myelin-associated glycoprotein

• chondronitin sulphate proteoglycans

• neurotoxic factors

Which of the following statement is correct?

• Tidy injury is the most common type of CNS injury

• Olfactory segments transplantation can help patients with myasthenia gravis.

• Myelin droplet formation in the first stage of peripheral nerve regeneration inhibits the recovery of nerve.

• Untidy injury has the worst outcome among all types of injury

• Penumbra in stroke refers to the area of irreversible damage and neuronal death.

Which of the following about Myasthenia gravis is incorrect?

• It is due to the damage of the interneuronal junction.

• Drooping eyelids and double vision are common clinical presentations.

• Predisolone can suppress the antibodies that attack the receptors.

• Neostygmine can inhibit acetylcholinesterase to relieve the symptoms.

• It can be diagnosed with ice test.