Endo Exam 2 - Frucose, Sorbitol Corso

What are the most important products of the pentose phosphate pathway

• ATP
• glucose
• NADH
• NADPH
• ribose-5-phosphate

What glycolysis intermediate is the starting point for PPP

• glucose
• glucose-6-phosphate
• fructose-6-phosphate
• glyceraldehyde-3-phosphate
• pyruvate

What are the products of the non-oxidative phase of PPP that return to glycolysis

• glucose
• glucose-6-phosphate
• fructose-6-phosphate
• glyceraldehyde-3-phosphate
• 1,3-bisphosphoglycerate

Which enzyme in the PPP is dependent on thiamine

• glucose-6-phosphate dehydrogenase
• gluconolactonase
• transketolase<br />
• transaldolase<br />
• pentose phosphate isomerase

What is glutathoine needed for

• it is a building block of a protein
• it is an antioxidant needed to neutralize peroxide
• it is an oxidizing agent needed to make ATP
• it is needed as a component of hemoglobin

A defect of the enzyme glucose-6-phosphate dehydrogenase most commonly causes

• enlarged liver
• hemolytic anemia
• hypoglycemia
• hyperglycemia

In G6PDD, what reducing equivalent is missing

• FADH2
• NADH
• NADPH

Which enzyme requires NADPH as a reducing agent

• glutathione reductase
• PFK-1
• hexokinase
• transketolase<br />

A well nourished physician of Mediterranean heritage is suffering fatigue while doing missionary work in Africa. This physician doesn't have a history of heavy alcohol consumption. Shortly after receiving an anti-malarial drug, symptoms started to appear. Lab tests indicate low RBCs and a urine test indicates the presence of free hemoglobin. Which of the following conditions would best explain these symptoms

• Beta-galactosidase deficiency
• galactosemia
• glucose-6-phosphate dehydrogenase deficiency
• Aldolase B
• niacin deficiency

An alcoholic of northern European descent shows that he has borderline hemolytic anemia. A blood test shows a decreased in the rate of the enzyme transketolase, but a genetic test shows that there is no genetic defect with this enzyme. Supplements with which vitamin is most likely to improve this patien's condition

• Vitamin A
• Riboflavin
• Niacin
• Thiamine
• Biotin