AP BIO: Signal Transduction Pathways Review

What are the three parts of signal transduction pathway?

• reception, transduction, response

• confirmation, transduction, transcription

• reception, amplification, transcription

• confirmation, amplification, response

Transduction step traditionally amplifies the signal, which of the following are NOT involved with transduction?

• secondary messengers

• protein modification

• phosphorylation cascade

• ligands

Which of the following is NOT a response by the cell from a signal transduction pathway?

• cell growth

• gene expression

• secretion of molecules

• all of the above are responses

Describe what occurs when the ligand binds to the receptor.

• confirmation change in shape of receptor

• phosphorylation of ligand

• ligand passes through the membrane

• receptor binds additional ligands

Describe the impact of a mutation in any domain of the protein components of the transduction pathway.

• receptor unable to bind to ligand

• no changes in transduction due to initial signal transduction from ligand

• alters response of the cell

• amplification of signaling pathway to bind more ligands

Tags

NGSS.HS-LS3-2

In a signal transduction pathway, the signal activates a(n)

• receptor

• hormone

• effector molecule

Signals that travel to distant cells through the circulatory system are known as

• neurotransmitters

• white blood cells

• hormones

In general, all cell signaling causes

• increased expression of genes.

• an influx of ions.

• protein kinase activity.

• a change in receptor conformation

What is the role of protein kinase in a signal transduction pathway?

• activates a molecule by adding a phosphate to the target molecule

• deactivate a molecule by removing a phosphate from the target molecule

• activates a molecule by removing a phosphate from the target molecule

• deactivate a molecule by adding a phosphate to the target molecule

Once a cell responses to a signal, what would need to occur to stop the response?

• activate the relay proteins

• deactivate the relay proteins

• destroy the cell

• genetically modify the DNA of the cell

Tags

NGSS.HS-LS1-3