Uses and Administration of Blood and its Components

Packed RBCs have been requested:
Patient: Group A negative, has anti-Fya.

What would you give the patient?

• O positive

  Fya negative

• O negative

  Fya negative

• A negative

  Fya positive

• A positive

  Fya negative

Whole blood units were requested.

Patient: AB Positive

Which of the following options is(are) suitable?

• O Neg whole blood bag

• AB Pos whole blood

• O Pos whole blood

• Both AB Pos and O Neg whole blood are compatible

URGENT!! RBC packs were requested for 2 female patients (2 packs for each). ABO and Rh unknown

Patient 1: 30 year old female

Patient 2: 60 year old female

Blood bank only had 2 O neg RBCs and 2 O pos RBCs

What would you do??

• give the 60 year old the O neg

• give the 30 year old the O neg

• give 1 unit of O neg and 1 unit of O pos to each paient

AHG phase of a crossmatch detects ABO incompatibility.

• TRUE

• FALSE

A patient had a previous record showing:

Patient: B Positive, has anti-C.

2 units of packed RBCs were requested.

• Issue B Rh D neg, C neg, and computer crossmatch

• issue O neg, IAT crossmatch

• Issue B Rh D neg, C neg, and perform serologic crossmatch

• issue B RhD neg, computer crossmatch

Group B RhD Positive patient was given large amounts of group O RhD positive red cell concentrates, then a crossmatch was performed with group B RBC unit which came up positive.

Additional RBCs have been requested. what should the patient be given?

• B RhD positive RBCs

• Give them volume expander instead

• AB RhD negative RBCs

• O RhD positive RBCs

Clinically significant antigens are?

• antigens capable of eliciting an immune response

• antigens capable of lysing red cells

• antigens present on almost all red cells

Why is the antibody's ability to activate complement essential in the blood bank?

• Because complement is a sign of a transfusion reaction

• Because it is a potent cell lysis pathway

• Because complement is expressed abundantly on RBC surface

What are the three most important mechanisms of RBC destruction? 

• complement activation

• antigen mediated apoptosis

• antibody dependent cellular cytotoxicity

• phagocytosis

Highlight all correct statements

• RBCs are used to improve oxygen levels

• platelets are used to compensate for clotting factors

• plasma may be used for volume replacement

• RhIg is used on Rh positive women to prevent Rh HDN