SOUMIK PATRA_MPT1062_MCQ1

Matrix system is widely used for

• Controlled release drug delivery system

• Sustain release drug delivery

  system

• Delayed release

  system

• Extended release system

In matrix system hydrophilic polymers are used as-

• Gelling agent

• Mixing agent

• Binding agent

• Swelling agent

Major draw backs of conventional dosage form are

• Increased chances of missing the dose of a drug with short half-life for which frequent administration is necessary

• The unavoidable fluctuation of drug concentration may leads to under medication or over medication

• Bioavailability is very high

• Poor patient compliance

What are the challenges to sustained release drug delivery

• Biocompatibility

• Cost of formulation, Preparation and processing

• Fate of controlled release system if not biodegradable

• Fate of polymer additives

A dose of drug is initially is released immediately after administration, equal to the single dose and after a certain period a second single dose is release. This is known as

• Sustained release

• Repeat action

• Controlled release

• Delayed release dosage form

Pharmaceutical dosage forms release the drug slower than normal manner at predetermined rate and necessarily reduce the dosage frequency by two folds are known as-

• Controlled release

• Sustained release

• Repeat action

• Extended release

Enteric coated tabled is a type of-

• Controlled release

• Sustained release

• Delayed release dosage form

• Extended release

Suitable drug for sustained release drug delivery system shoul have

• High apparent partition coefficient

• Low apparent partition coefficient

• No relation with partition coefficient

• Very poor apparent partition coefficient

The absorption mechanism of drug suitable for sustained releasse drug delivery system should be

• Dissolution

• Disintegration

• Diffusion

• None

The dosage form is released the drug in a planned, predictable and slower than conventional dosage form is known as-

• Controlled release dosage form

• Sustained release dosage form

• Prolonged released dosage form

• Extended releasse dosage form