Hematologic System

Which of the following medications should be used as an injectable outpatient therapy for blood clot

prevention?

• Enoxaparin (Lovenox)

• Alteplase (Activase)

• Warfarin (Coumadin)

• Tirofiban (Aggrastat)

A patient asks a pharmacy technician how fondaparinux (Arixtra) functions. Which of the following

responses should the technician make?

• “The medication acts by inhibiting clotting factor Xa in the body, which inhibits blood

  coagulation.”

• “The medication affects platelets from clumping together by blocking glycoprotein IIb

  receptors.”

• “The medication breaks down clumps of thrombocytes by increasing production of natural

  antiplatelets.”

• “The medication prevents thrombus formation by inhibiting plasmin and fibrinogen.”

If a patient misses a dose of an anticoagulant medication, the patient might be at risk for which of the

following symptoms?

• Blood clots

• Bleeding

• Pain

• Difficulty breathing

Which of the following conditions is caused by the dislodging of a blood clot and can result in

difficulty breathing?

• Hemophilia

• Pulmonary embolism

• Angina

• Peripheral artery disease

A patient receives eptifibatide (Integrilin) in the hospital and asks a pharmacy technician how the

medication works. Which of the following responses should the technician make?

• “It inactivates the enzyme responsible for degrading fibrin proteins.”

• “It prevents platelets from binding and clumping together.”

• “It increases the production of fibers to increase coagulation.”

Which of the following substances is responsible for forming a platelet plug during coagulation?

• Thrombin

• Thrombocyte

• Plasmin

• Neutrophil

Which of the following terms is used to describe a dislodged deep-vein thrombosis?

• Hemophilia

• Thrombocytopenia

• Hypoxia

• Embolism

Swelling and pain in the leg are symptoms of which of the following conditions?

• Erythropoiesis

• Pulmonary embolism

• Deep vein thrombosis

• Granulocytosis

Which of the following proteins is responsible for blood coagulation, works in the clotting cascade,

and stimulates platelet activation?

• Coronin

• Fibrinogen

• Prothrombin

• Thrombin

Which of the following processes prevents the clotting of blood?

• Platelet deactivation

• Anticoagulation

• Coagulation

• Platelet disaggregation