Genetic Mutations

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

• Substitution

• Deletion

• Insertion

• Frameshift

A mutation is defined as:

• A change in the cell's structure

• Anything that changes in an embryo

• Any change in the physical features of a human

• A change in the DNA sequence

A change in a gene, group of genes or chromosome that results in a change in the proteins

• Replication

• Mutations

• Translation

• Transcription

Are all mutations bad?

• Yes
• No

Why is the order of amino acids so important?

• The order of amino acids dictates what shape the protein will fold into.
• It is not important. The protein folding chamber will force the protein to fold into the correct shape.

What is a Gene?

• A segment of RNA that encodes for a protein
• A chromosome
• A segment of DNA that encodes for a protein
• Your genome

Trisomy 21, or having 3 copies of chromosomes 21 is known as which type of mutation?

• Point

• Trinucleotide Repeat Expansion

• Nondisjunction

• Gene Translocation

When a nucleotide is added to a DNA sequence, which of the following will occur?

• Point Mutation

• Silent Mutation

• Frameshift Mutation

• Gene Duplication

What type of mutation is shown in the image?

• Frameshift

• Nondisjunction

• Trinucleotide Repeat Expansion

• Silent Mutation

Mutation that occur in _________ cells are passed from parents to offspring.

• Somatic

• Germ

• Brain

• Genotypic