NDDS-01

One of the following is not an advantages of NDDS.

• Patient Compliance

• Steady State Plasma Conentration

• Less drug of dose

• Chance of dose dumping

One of the following is not a type of CDDS

• Rate-programmed DDS

• Stimuli-activated DDS

• Site-targeted DDS

• None of the above

Correct statement regarding an Ocusert system is

• it is a tablet taken orally

• it is meant to be insert in cul-de-sac cavity

• It is example of Osmotic DDS

• It is example of Transdermal DDS

Which of the osmogen used in an osmotic controlled drug delivery system

• Sodium chlorid

• Propylene glycol

• Poly vinly acetate

• Polly vinyl pyrollidone

Mainly drugs are absorbed through skin by one of the processes

• Passive diffusion

• Active tranport

• Filteration

• Carrier transport

Chose the drawback of using CDDS

• Prompt termination of therapy is not possible

• Prevention of side effects

• Risk of dose dumping

• Maintenance of drug levels within a desired range

Following are the physiological (Physicochemical) factors affecting on CDDS, except

• Aqueous solubility

• Drug pKa

• Biological Half-life

• §Protein binding

The rate-limiting steps for the controlled release dosage form

• Dissolution

• Drug release from the dosage form

• Drug absorption

• Drug penetration

A good drug candidate for controlled drug delivery should have half-life of

• 2-6 hr

• 8-12 hr

• Less than 2 hr

• More than 24 hr

___________selected to release the drug in controlled manner, at a predetermine rate and predetermine time.

• Orally disintegrating drug delivery system

• Fast drug delivery system

• Immediate release DDS

• Controlled DDS