Resp - Exam 2 - COPD Broncho Keshvara

What are some characteristics of COPD

• more obstructive compared to asthma

• less obstructive compared to asthma

• chronic inflammation predominantly in smaller airways

• very responsive to corticosteroids

• minimally responsive to corticosteroids

What are some characteristics of COPD

• small airway narrowing & fibrosis

• destruction of alveolar walls & lung parenchyma

• destruction of only airways

• excessive mucus production

• no mucus production

What are some symptoms of COPD

• increased breathlessness

• frequent coughing (with or without mucus)

• wheezing

• tightness in chest

Systemic manifestations occur in both COPD and asthma

• true

• false

Answer explanation

COPD has systemic manifestations that are not found in asthma

What are some systemic manifestations of COPD

• skeletal muscle wasting

• weight loss

• depression

• osteoporosis

• ischemic heart disease

What are some major cellular components of COPD

• eosinophils

• mast cells

• cytotoxic T lymphocytes (Tc1)

• neutrophils

• macrophages

Helper T cells cause persistent damage to lung tissues

• true

• false

Answer explanation

Cytotoxic T lymphocytes (Tc1) cause persistent damage to lung tissues

Which cellular components act like they are trying to get rid of bacteria that is not there which ends up destroying tissue

• eosinophils

• mast cells

• cytotoxic T lymphocytes (Tc1)

• neutrophils

• macrophages

What are some noncellular components that effect COPD

• leukotrienes

• histamines

• proteases

• mucus hypersecretion

• no mucus secretion

Answer explanation

Non-cellular components:

- different set of mediators (than asthma)

- proteases (alveolar wall damage)

- mucus hypersecretion

What noncellular component causes alveolar wall damage in COPD

• leukotrienes

• histamines

• proteases

• mucus hypersecretion

• no mucus secretion