Topic 5 Cell signalling

In response to a signal begin received a cell may ________.

• Grow and divide

• Survive

• Die

• All of the above

Signalling from local mediator cell to targets in close proximity is an example of which kind of signalling?

• Endocrine

• Paracrine

• Neuronal

• Contact dependent

The speed of a response to an extracellular signal depends apon.....

• The mechanism of signal delivery

• Whether transcription is required

• Whether protein function is altered

• All of the above

In the signal transduction pathway the signal is passed though the cytoplasm via....

• Extracellular signalling molecules

• Effector proteins

• Receptor proteins

• Intracellular signalling molecules

GTP proteins switch between active state (GDP bound) and inactive state (GTP bound)

• TRUE

• FALSE

Cyclic AMP is synthesised by adenyl cyclase and degraded by ......

• Phospholipase C

• PKA

• cyclic AMP phosphodiesterase

• cyclic AMP phospholipase C

RTKs are an example of enzyme coupled receptor but what does it stand for?

• Retinol transfer kinase

• Receptor tyrosine kinase

• Receptor threonine kinase

• Receptor transferase kinase

During PI3-AKT pathway, activated AKT promotes what?

• Cell survival

• Cell death

• Cell differentiation

Different signals originating from the plasma membrane can be integrated by cross talk between different signalling pathways inside the cell.

• TRUE

• FALSE

Signalling molecules fall into 2 classes based on what?

• Size and charge

• Size only

• Charge only

• Chain length