TDM測驗題
Authored by 駿誼 吳
Science
Professional Development
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20 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 5 pts
Theophylline主要經由哪個酵素代謝?
CYP1A2
CYP2C9
CYP2C19
CYP3A4
2.
MULTIPLE CHOICE QUESTION
30 sec • 5 pts
藥品需要做濃度監測的原因？
此類藥品的治療指數 (Therapeutic index) 狹窄
此類藥品單價較高
此類藥品給付規定較嚴格，需密切注意用量
此類藥品的代謝較複雜
3.
MULTIPLE CHOICE QUESTION
30 sec • 5 pts
Valproic acid 蛋白結合率高，與下列何種藥物較不會有蛋白競爭的交互作用
Theophylline
Warfarin
Carbamazepine
Phenytoin
4.
MULTIPLE CHOICE QUESTION
30 sec • 5 pts
Valproic acid的建議濃度範圍為?
50-100 μg/mL
50-100 μg/L
20-50 μg/mL
20-50 μg/L
5.
MULTIPLE CHOICE QUESTION
30 sec • 5 pts
下列何種TDM監測藥物，本身具有自我誘導代謝的功能，因此達到穩定濃度的時間較長
Carbamazepine
Valproic acid
Phenobarbital
Tacrolimus
6.
MULTIPLE CHOICE QUESTION
30 sec • 5 pts
計算藥品新劑量時，會使用多次劑量給藥的計算公式，請問公式中的參數何者錯誤？
Cpss：穩定狀態血中藥物濃度 (Steady-state concentration)
Cl：清除率 (Clearance)
F：生體可用率(bioavailibility)
S：輸注速率 (Infusion rate)
7.
MULTIPLE CHOICE QUESTION
30 sec • 5 pts
下列何者不是Valproic acid濃度過高時可能產生的不良反應
心律不整
血小板低下
高血氨
嗜睡，嚴重時可能昏迷
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