Unit 7 Review

This pedigree shows hemophilia. What can you assume about hemophilia?

• It is dominant.

• It is multiple alleles.

• It is sex-linked.

• It is co-dominant.

This is a karyotype of a female. It shows a disorder. The mutation occurred most likely because of:

• an insertion of chromosome 11

• a deletion of chromosome 3

• a missing X chromosome

• a missing Y chromosome

Sickle cell is an autosomal recessive genetic disorder that has abnormally shaped red blood cells. How do people get this trait in their gene pool?

• Heterozygous parents pass on the dominant allele.

• Homozygous dominant parents pass their recessive allele.

• Homozygous dominant parents pass on their dominant allele.

• Heterozygous parents pass on their recessive allele.

Which genetic disorder can block the veins and prevent oxygen from flowing?

• Sickle Cell Disease

• Cystic Fibrosis

• Down syndrome

• Hemophilia

How could identical twins show different traits when their DNA is identical?

• They have a lot of mutations.

• Their environment impacts their genes.

• They make different proteins.

• They have different mRNA.

This pedigree shows PKU. How did person 3 in the 2nd generation get PKU?

• inherited 2 recessive alleles from each carrier parent

• inherited a dominant allele from each parent

• inherited it through a mutation

• inherited a sex linked allele from Mom

Substitutions occur when one base is exchanged for another. This can cause no change in some situations, but can make a different protein in other situations. How?

• All codons make different proteins.

• Insertion can help create proteins in some situations that are different.

• Deletion can help make different proteins and substitution makes the same proteins.

• Amino acids can be the same for some codons, but can make different proteins in others.

My brother and I grew up in the same house, went to the same school, and ate the same foods. Why did I get allergies and he didn't?

• I must have a weak immune system.

• I must be older than my brother.

• My brother must have a higher metabolism.

• I must be genetically different than my brother.

Which genetic disorder occurs because one amino acid is changed and impacts the protein made in hemoglobin?

• Sick Cell Disease

• Hemophilia

• Cystic Fibrosis

• Down's syndrome

CF is autosomal recessive. If both parents are heterozygous, what is the chance of them having offspring that are carriers?

• 25%

• 50%

• 75%

• 100%