Gene Mutations

A substitution mutation that has no effect

on an amino acid's sequence would be best categorized as:

• Insertion Mutation

• Translocation

• Silent Mutation

• Deletion Mutation

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

A change in a DNA sequence from ACGTGGCA to AGTGGCA would best be described as

• Insertion

• Frameshift

• Substitution

• Duplication

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

A nucleotide base is inserted or deleted shifting the entire DNA sequence. In this instance, the entire protein will be changed. Which of the following best describes this type of mutation?

• Substitution Mutation

• Silent Mutation

• Frameshift Mutation

• Translocation

Tags

NGSS.HS-LS3-2

The image shown depicts a point mutation. Which of the following categories best describes this mutation?

• Missense

• Nonsense

• Silent

• Neutral

Tags

NGSS.HS-LS3-2

Layla is typing on an old typewriter. As she looks at her work, she realizes that the "v" key is not working. Therefore, when she tries to type the word "favorable," she actually types "faorable." This example is an analogy to which of the following types of mutations?

• Deletion

• Insertion

• Substitution

• Duplication

Tags

NGSS.HS-LS3-2

The DNA strand TAC GCG ATT results in the mRNA strand AUG CGC UAA. If a base in the first codon undergoes a substitution mutation, what would likely happen to the amino acid that this segment of DNA codes for?

• It would be twice as long as it was supposed to be

• It would only produce one amino acid

• This gene would not be translated

• All three codons would be altered

Answer explanation

Remember, you only have ONE start codon - if your ribosome cannot locate that start signal, there will not be any translation of that gene.

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

ORIGINAL DNA: TACGCATGC

NEW DNA: TACGCCATGC

What type or types of mutations are observed in this example?

SELECT ALL THAT APPLY

• Insertion

• Deletion

• Substitution

• Frameshift

• Point

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

How many nucleotides are involved in a point mutation?

• 1

• 2

• 3

• 4

Tags

NGSS.HS-LS3-2

A mutation in the third base of a codon for the amino acid Proline (Pro) will always be a silent mutation. Which of the following pieces of information best supports this claim?

• Proline is always made from the same 3 bases

• As long as the first two bases on the mRNA codon are both C, it will always code for proline; regardless of the 3rd base

• Proline is a stop codon, so it isn't actually an amino acid and therefore cannot be mutated

• Proline has evolved to become resistant to harmful mutations

Tags

NGSS.HS-LS3-2

Which of the following types of mutations will impact the FEWEST codons?

• Substitution

• Insertion

• Deletion

• Frameshift