BETA LACTAM ANTIBIOTICS

A 70 year old man comes with fever and extensive skin lesions. Investigations reveal presence of gram positive cocci in the skin lesions. The most appropriate drug to treat this patient is:

• Amoxycillin

• Cloxacillin

• Penicillin G

• Piperacillin

A 45 year old woman with second degree burns has now been infected with a greenish color pus which shows presence of Pseudomonas .Which of the following drugs can be used for her?

Penicillin G does NOT act by which of the following mechanisms:

• Inhibition of transpeptidases

• Inhibition of beta lactamases

• Inhibition of P.B.P.

• Stimulation of autolysins

A 75 year old man is brought to the E.R. with high grade fever and loss of sensorium over the past 2 days .Investigations reveal presence of Listeria monocytogenes in the C.S.F. The treatment of choice for this patient will be:

Which of the following statement is false about beta lactamase inhibitors?

• Clavulanic acid combined with ticarcillin has to be given parentally

• Their usage can broaden  the  spectrum of antibiotic

• Very effective in treating infection by beta lactamase producing Pseudomonas

• They may cause GIT upsets,rashes

Which of the following statements are CORRECT regarding cephalosporins?

 

• They are bacteriostatic for sensitive strains

• Bleeding tendencies can be encountered as adverse effects due to cephalosporins

• They are bactericidal inhibitors of protein synthesis

• The third generation cephalosporins mainly target gram positive organisms

A 5 year old girl with high grade fever has been diagnosed to be suffering from Salmonella typhi. The best treatment option for her is............................................. 

A 25 year old woman is to undergo a surgery due to a gynecological problem Which of the following broad spectrum antibiotic  will be commonly prescribed to her prior to surgery as a prophylaxis  against infection?

• a)Piperacillin

• b)Cefazolin

• Azithromycin

• Cotrimoxazole

Which one of the following cephalosporin may MOST LIKELY cause disulfiram like reaction?

• Cefepime 

• Ceftriaxone. 

• Cefazoline 

• Cefaperazone

The cephalosporin most likely to cause bleeding as an ADR is: